Mycoplasma Removal Reagent (MRA)

  • Mycoplasma Removal Reagent (MRA)IN0003

Mycoplasma Removal Reagent (MRA)IN0003

  • Packing specification

    Product number: IN0003

    Specifications: 1mL1000×)5mL1000×)

    Storage conditions

    Store at 4℃ in the dark for 2 years, avoid repeated freezing and thawing

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Product description:

Mycoplasma, also known as mycoplasma, belongs to the class of Lapis. It has no cell wall, nor can it synthesize cell wall precursors. It has a three-layer structure of unit membrane, which cannot maintain a fixed form and exhibits polymorphism. It exists widely in nature, with more than 80 Species, the most common Mycoplasma that contaminate cells include Mycoplasma fermentum, Mycoplasma hyorhinis, Mycoplasma oral cavity, Mycoplasma arginine, Mycoplasma pear, Mycoplasma salivarius, and Mycoplasma hominis. Mycoplasma usually attaches to the surface of cells and affects the physiology, genetics and other normal functions of their host cells. Using these contaminated seemingly normal cells for experiments or production will seriously affect the results.

Mycoplasma scavenger is an effective method to solve the serious problem of mycoplasma contamination in cell culture. This reagent is an antibiotic derivative, which removes mycoplasma infection by inhibiting mycoplasma DNA gyrase helicase. In the recommended concentration, it can effectively remove a variety of mycoplasma and prevent the recurrence of mycoplasma pollution. It has a strong ability to inhibit the activity of mycoplasma and can completely remove mycoplasma from contaminated cultured cells within a week.

1). Specific and strong ability to inhibit the activity of mycoplasma, completely remove mycoplasma from contaminated culture: remove mycoplasma pollution by inhibiting DNA gyrase, which is an indispensable enzyme in the process of microbial DNA replication.

2). Wide range of activity: the activity can be maintained for up to 7 days in cell culture, and has an effect on a variety of mycoplasma strains.

3). Low concentration, low cytotoxicity: using at the recommended concentration, cytotoxicity is minimal, so it can also be used as a reagent to prevent mycoplasma contamination. Experiments show that compared with similar products of other brands, it has no lethal effect on normally cultured cells.

4). Prevent the recurrence of mycoplasma contamination: Once used, the cultured cells will no longer be contaminated by the same mycoplasma, thereby preventing the recurrence of contamination.

5). Easy to use: It is very convenient to use, it is ready to use, just add it to the cultured cells contaminated by mycoplasma and incubate for one week.

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